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| Ibandronic acid ： ウィキペディア英語版 |
Ibandronic acid
Ibandronic acid (INN) or ibandronate sodium (USAN) is a potent bisphosphonate drug developed by Hoffman La Roche and used in the prevention and treatment of osteoporosis and metastasis-associated skeletal fractures in people with cancer. It may also be used to treat hypercalcemia (elevated blood calcium levels). Global sales in 2008 were 1.1B CHF ($1.0B USD at 01/01/2009 exchange rates).〔
(【引用サイトリンク】accessdate=2009-08-13 )〕
==Medical uses==
Ibandronate is indicated for the treatment and prevention of osteoporosis in post-menopausal women.〔(【引用サイトリンク】url=http://www.drugs.com/monograph/boniva.html )〕 In May 2003, the U.S. Food and Drug Administration (FDA) approved Ibandronate as a daily treatment for post-menopausal osteoporosis. The basis for this approval was a three-year, randomized, double-blind, placebo-controlled trial women with post-menopausal osteoporosis. Every participant also received daily oral doses of calcium and 400IUs (units ) of vitamin D. At the study's conclusion, both doses significantly reduced the occurrence risk of new vertebral fractures by 50–52 percent when compared to the effects of the placebo drug.
Ibandronate is efficacious for the prevention of metastasis-related bone fractures in multiple myeloma, breast cancer, and certain other cancers.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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